Louise Ince

Projects

I aim to understand the interactions between the circadian and neuroimmune systems, and to determine how circadian disruption impairs cognition via neuroinflammatory mechanisms (e.g., in aging and pathology).

Circadian clocks in microgliaHow does the microglial clock regulate neuroinflammation?

Using cell-specific disruption of the key clock element Bmal1, I am testing how microglial clocks regulate neuroinflammatory responses and behavior.

Novel approaches to increase healthspanCan we live better longer by harnessing our circadian system?

I am testing how time-restricted feeding modulates neuroinflammation and behavior in aging.